When you use the keyboard shortcuts to take screen grabs in OS X the default is to save them to the Desktop. If you are like me and you use these keys a lot, your desktop will quickly become crowded. What you need to do is change the default folder for screen shots.
I don’t know why this isn’t a System Preference but it’s pretty simple to change the defaults with a little Terminal-fu.
1. Open an OS X Terminal (Go to Utilities->Terminal)
2. Inside the terminal, issue the following command
defaults write com.apple.screencapture location /DESTINATION
where DESTINATION is the directory you wish to save to.
3. Logout and Log back in.
So, for example, if you create a Screenshots folder inside the Pictures directory your command would look like this:
defaults write com.apple.screencapture location ~/Pictures/Screenshots
That’s all there is to it. If you have any interesting system tweaks, let us know in the comments.